This study attempts to find a link between years of life lost and life-years lost from diabetes and cardiovascular disease associated with excess bodyweight. To address this concern, Steven A Grover, Mohammed Kaouache, Philip Rempel, Lawrence Joseph, Martin Dawes, David C W Lau, and Ilka Lowensteyn developed a disease-simulation model to estimate the annual risk of diabetes, cardiovascular disease, and mortality for people with BMI of 25<30 kg/m2 (overweight), 30<35 kg/m2 (obese), and 35< higher (very obese) all in comparison to an ideal BMI of 18.5-25 kg/m2. They were able to use 3,992 non-Hispanic, white participants in the National Nutrition and Examination Survey, spanning from 2003-2010. For them, complete risk factor data and fasting glucose concentrations were available. They estimated the years of life lost and healthy life-years associated with each body weight category.
Findings: Excess bodyweight was positively associated with risk factors for cardiovascular disease and type 2 diabetes. The effect of excess weight on years of life lost was greatest for younger individuals and decreased as age increased. For obese men, the years of life lost ranged from 0.8 years aged 60-79 years and 5.9 years for those aged 20-39. Years lost for every obese man ranged from 0.9 years to 8.4 years. Losses were much smaller for those in the overweight category in comparison to the obese categories. There were similar results for women, such as 6.1 years lost for every obese woman aged 20-39 and only 0.9 years lost for obese women aged 60-79. Healthy life-years lost were two to four times higher than total years of life lost for all age groups in each weight category. To clarify, years of life lost mean years of life lost. Healthy life-years lost are years the years free from cardiovascular disease and diabetes.